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THE CRITICAL INTERPLAY BETWEEN SLEEP AND IMMUNITY

Category Review Article
Authors Dhastagir Sultan Sheriff, Ranji Jha, Anna Medical College, Mauritius drdsheriff@gmail.com
Abstract Sleep is a natural state of rest and a restorative process for the mind and body. For ages, it has been believed that someone deprived of sleep is more likely to acquire infections and other pathologies, highlighting its role as an important immune modulator. In recent years, sleep disorders and declining sleep quality have become increasingly prevalent. We also know that immune responses during immune activation affect cytokines that control sleep architecture. Sleepiness and dizziness are common symptoms of fever and infections. Diseases like autoimmune disorders or chronic infections are associated with disrupted sleep, including fragmented sleep and insomnia. While immune activation affects sleep, poor sleep can also impair immune function, creating a cycle that increases both sleep disturbances and health issues. This review summarizes information on the reciprocal relationship between sleep and immunity. This area of research has important implications for public health, as lack of sleep can lower immunity in the population. Knowing the value of this relationship is crucial, as it impacts both individual well-being and societal health. By elucidating the complex interactions between sleep and the immune system, this review highlights the importance of addressing sleep issues to improve overall health outcomes.
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